Metformin hydrochloride, aka metformin HCL, is an oral medication primarily prescribed to help people with type 2 diabetes lower their blood sugar. Metformin HCL 500 mg is the lowest dose of this medication. Learn about side effects, how it's taken, and more of metformin. It's a generic prescription drug that's used to help manage blood sugar levels in adults and some children with type 2 diabetes. Metformin is a commonly recommended initial medication for patients with type 2 diabetes who have mild to moderately uncontrolled blood glucose. In addition, it is sometimes used to prevent diabetes in patients who are at risk of developing the disease (though it is not FDA approved for prediabetes). Metformin package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology. Metformin is a biguanide antihyperglycemic agent used for treating non-insulin-dependent diabetes mellitus (NIDDM). It improves glycemic control by decreasing hepatic glucose production, decreasing glucose absorption and increasing insulin-mediated glucose uptake. Metformin is used to treat high blood sugar levels that are caused by a type of diabetes mellitus or sugar diabetes called type 2 diabetes. With this type of diabetes, insulin produced by the pancreas is not able to get sugar into the cells of the body where it can work properly. This article describes the dosages of metformin, as well as its strengths and how to take it. When taking metformin, always follow the dosage prescribed by your doctor. Metformin is an FDA-approved antidiabetic agent that manages high blood sugar levels in type 2 diabetes patients. It reduces glucose absorption from the intestines, lowers liver glucose production, and improves insulin sensitivity. Overview: Metformin is medicine you take to help keep your blood sugar from getting too high. Common side effects may include stomach problems, such as diarrhea, nausea, vomiting, stomach pain. Metformin hydrochloride (1,1-dimethylbiguanide hydrochloride) is freely soluble in water, slightly soluble in ethanol, but almost insoluble in acetone, ether, or chloroform.