Metformin is a first-line treatment used for type 2 diabetes in adults and children 10 years and older to help improve blood sugar levels. It is also used off-label to improve symptoms of polycystic ovarian syndrome (PCOS) and other conditions. Metformin is a biguanide antihyperglycemic agent used for treating non-insulin-dependent diabetes mellitus (NIDDM). It improves glycemic control by decreasing hepatic glucose production, decreasing glucose absorption and increasing insulin-mediated glucose uptake. Metformin helps manage blood sugar in type 2 diabetes. WebMD reviews common side effects, extended-release benefits, vitamin B12 risks, and precautions. Overview: Metformin is medicine you take to help keep your blood sugar from getting too high. Common side effects may include stomach problems, such as diarrhea, nausea, vomiting, stomach pain. Metformin hydrochloride (1,1-dimethylbiguanide hydrochloride) is freely soluble in water, slightly soluble in ethanol, but almost insoluble in acetone, ether, or chloroform. Easy-to-read patient tips for metformin covering how it works, benefits, risks, and best practices. Metformin is used together with proper diet and exercise to treat high blood sugar levels caused by type 2 diabetes. This medicine reduces the absorption of sugar from the intestines, reduces the release of stored sugar from the liver, and helps your body use sugar better. Metformin is a prescription medication used to treat the symptoms of Type 2 Diabetes Mellitus. Learn about side effects, dosages, drug interactions, and more. Metformin is a generic prescription medication used to help manage blood sugar levels in adults and some children with type 2 diabetes. It works by decreasing sugar production in the liver. Metformin hydrochloride, aka metformin HCL, is an oral medication primarily prescribed to help people with type 2 diabetes lower their blood sugar. Metformin HCL 500 mg is the lowest dose of this medication.